2. Cell Cycle/DNA Damage Cytoskeleton Antibody-drug Conjugate/ADC Related
  3. Microtubule/Tubulin Drug-Linker Conjugates for ADC
  4. AmPEG6C2-Aur0131

AmPEG6C2-Aur0131 is a agent-linker conjugate for ADC (anti-CXCR4 ADC) with potent antitumor activity by using Aur0131 (an auristatin microtubule inhibitor), linked via the non-cleavable linker AmPEG6C2.

For research use only. We do not sell to patients.

AmPEG6C2-Aur0131 Chemical Structure

AmPEG6C2-Aur0131 Chemical Structure

CAS No. : 1650569-94-0

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AmPEG6C2-Aur0131 Related Antibodies

Top Publications Citing Use of Products

View All Drug-Linker Conjugates for ADC Isoform Specific Products:

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Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

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Description

AmPEG6C2-Aur0131 is a agent-linker conjugate for ADC (anti-CXCR4 ADC) with potent antitumor activity by using Aur0131 (an auristatin microtubule inhibitor), linked via the non-cleavable linker AmPEG6C2[1].

IC50 & Target

Traditional Cytotoxic Agents

 

Molecular Weight

1065.34

Formula

C54H92N6O15
CAS No.
SMILES

NCCOCCOCCOCCOCCOCCOCCC(N1[C@@](C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@H]([C@H](OC)[C@@H](C)C(N[C@@H](CC3=CC=CC=C3)C(O)=O)=O)CCC2)=O)=O)=O)(C)CCC1)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AmPEG6C2-Aur0131 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AmPEG6C2-Aur01311650569-94-0Microtubule/TubulinDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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