1675201-90-7
1675201-90-7
Chemical Structure
BMS-8
- CAS No.: 1675201-90-7
- Formula:C27H28BrNO3
- Molecular Weight:494.42
IUPAC Name: 1-(3-bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid
InChIKey: QRXBPPWUGITQLE-UHFFFAOYSA-N
SMILES: CC1=C(C=CC=C1C2=CC=CC=C2)COC3=CC=C(C=C3Br)CN4CCCCC4C(O)=O
Biological Activity: BMS-8 inhibits the PD-1/PD-L1 interaction with IC50 of 7.2 μM. BMS-8, binds directly to PD-L1 and induces formation of PD-L1 homodimers, which in turn prevents the interaction with PD-1[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BMS-8 | 98.0% | BMS-8 inhibits the PD-1/PD-L1 interaction with IC50 of 7.2 μM. BMS-8, binds directly to PD-L1 and induces formation of PD-L1 homodimers, which in turn prevents the interaction with PD-1. | ||||||||||||||||||||
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References
Keywords
