1691221-67-6
Chemical Structure
APTO-253 hydrochloride
Synonym(s): LOR-253 hydrochloride; LT-253 hydrochloride
- CAS No.: 1691221-67-6
- Formula:C22H14FN5
- Molecular Weight:367.38
IUPAC Name: 2-(5-fluoro-2-methyl-1H-indol-3-yl)-1H-imidazo[4,5-f][1,10]phenanthroline
InChIKey: NIRXBXIPHUTNNI-UHFFFAOYSA-N
SMILES: CC(NC1=C2C=C(F)C=C1)=C2C3=NC4=C5C=CC=NC5=C6N=CC=CC6=C4N3
Biological Activity: APTO-253?(LOR-253) hydrochloride is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253?hydrochloride mediates anticancer activity via induction of Kruppel-like factor 4?(KLF4)?tumor suppressor. APTO-253?hydrochloride exhibits antiarthritic activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
APTO-253 hydrochloride | APTO-253?(LOR-253) hydrochloride is a small molecule that inhibits c-Myc expression, stabilizes G-quadruplex DNA and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253?hydrochloride mediates anticancer activity via induction of Kruppel-like factor 4?(KLF4)?tumor suppressor. APTO-253?hydrochloride exhibits antiarthritic activity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
