172277-82-6

J-104118 Chemical Structure
172277-82-6

Chemical Structure

J-104118

  • CAS No.: 172277-82-6
  • Formula:C28H26Cl2FNO5
  • Molecular Weight:546.41

IUPAC Name: (S)-2-(2-(((2S,3S)-4-(3,4-dichlorophenyl)-3-(2-fluoro-[1,1'-biphenyl]-4-yl)butan-2-yl)amino)-2-oxoethyl)succinic acid

InChIKey: NBRLADMQSZWKGO-XUEUYAKLSA-N

SMILES: O=C([C@H](CC(O)=O)CC(N[C@@H](C)[C@@H](CC1=CC=C(C(Cl)=C1)Cl)C2=CC=C(C(F)=C2)C3=CC=CC=C3)=O)O

Biological Activity: J-104118 is a potent and orally active squalene synthase (SQS) inhibitor with an IC50 of 0.52 nM. J-104118 inhibits cholesterol synthesis in mice. J-104118 can be used for cholesterol-lowering research[1].

Cat. No. Product Name Purity Description Pricing
HY-116595
J-104118 J-104118 is a potent and orally active squalene synthase (SQS) inhibitor with an IC50 of 0.52 nM. J-104118 inhibits cholesterol synthesis in mice. J-104118 can be used for cholesterol-lowering research.
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