172430-37-4
Chemical Structure
Metalnikowin I
Synonym(s): MetI
- CAS No.: 172430-37-4
- Formula:C80H128N26O22S
- Molecular Weight:1838.10
InChIKey: VWHICVNVRWEDOX-JNXLUYDJSA-N
SMILES: O=C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N1[C@@H](CCC1)C(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CCCNC(N)=N)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N4[C@@H](CCC4)C(N[C@@H](CCCNC(N)=N)C(N5[C@@H](CCC5)C(N6[C@@H](CCC6)C(N[C@@H](CC(N)=O)C(N[C@@H](CCSC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N
Biological Activity: Metalnikowin I (MetI) is a proline-rich antimicrobial peptide and DnaK inhibitor. Metalnikowin I can be derived from insects[1][2].
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Metalnikowin I | Metalnikowin I (MetI) is a proline-rich antimicrobial peptide and DnaK inhibitor. Metalnikowin I can be derived from insects. | |||||||||||||||||||||
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- [1]. Seefeldt AC, et al. Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome. Nucleic Acids Res. 2016 Mar 18;44(5):2429-38. [Content Brief]
- [2]. Welch NG, et al. (Re)Defining the Proline-Rich Antimicrobial Peptide Family and the Identification of Putative New Members. Front Chem. 2020 Dec 1;8:607769. [Content Brief]
Keywords
