173429-64-6
Chemical Structure
Aladotril
Synonym(s): BP1137
- CAS No.: 173429-64-6
- Formula:C21H23NO5S
- Molecular Weight:401.48
IUPAC Name: benzyl ((S)-3-(benzo[d][1,3]dioxol-5-yl)-2-(mercaptomethyl)propanoyl)-L-alaninate
InChIKey: JHQKLXNTEQHOHI-WMLDXEAASA-N
SMILES: O=C(OCC1=CC=CC=C1)[C@H](C)NC([C@@H](CS)CC2=CC=C(OCO3)C3=C2)=O
Biological Activity: Aladotril (BP1137) is the inhibitor for neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE), that ameliorates the cardiac hypertrophy in rats, without decreasing the blood pressure. Aladotril can be used in research about heart failure and cardiac remodeling after myocardial infarction[1].
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Aladotril | Aladotril (BP1137) is the inhibitor for neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE), that ameliorates the cardiac hypertrophy in rats, without decreasing the blood pressure. Aladotril can be used in research about heart failure and cardiac remodeling after myocardial infarction. | |||||||||||||||||||||
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Keywords
