176983-21-4
Chemical Structure
2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid
- CAS No.: 176983-21-4
- Formula:C30H46O5
- Molecular Weight:486.68
IUPAC Name: (1R,2R,4aS,6aS,6bR,8aR,11R,12aR,12bR,14bS)-1,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid
InChIKey: LJORXTIGOHMBOS-OTRVPSFMSA-N
SMILES: OC([C@]12[C@]([C@](O)([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)(C([C@@H](C4)O)=O)C)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
Biological Activity: 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid, a natural ursane-type triterpene, is a potent inhibitor of HIV protease (HIV Protease). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid is also an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid displays an inhibitory activity against nitric oxide production in Lipopolysaccharide (Lipopolysaccharides)-activated RAW 264.7 cells[1][2].
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2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid | 98.0% | 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid, a natural ursane-type triterpene, is a potent inhibitor of HIV protease (HIV Protease). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid is also an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid displays an inhibitory activity against nitric oxide production in Lipopolysaccharide (Lipopolysaccharides)-activated RAW 264.7 cells. | ||||||||||||||||||||
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