A new ursane-type triterpene, cymosic acid from Rosa cymosa
- J Asian Nat Prod Res. 2014;16(4):422-5. doi: 10.1080/10286020.2014.885507.
Affiliations
- 1. a College of Pharmaceutical Science, Zhejiang Chinese Medical University , Hangzhou 310053 , China.
PMID: 24597721
DOI: 10.1080/10286020.2014.885507
Abstract
A new ursane-type triterpene, cymosic acid (1) together with two known compounds, 3β,19α-dihydroxy-2-oxo-12-ursen-28-oic acid (2) and 2α,19α-dihydroxy-3-oxo-12-ursen-28-oic acid (3), were isolated from Rosa cymosa Tratt. The structure of compound 1 was elucidated by analyzing its ¹H and ¹³C NMR, ¹H-¹H COSY, HSQC, HMBC, NOESY, and HR-ESI-MS values. The three compounds were found to display moderate inhibitory activities against nitric oxide production in lipopolysaccharide-activated macrophage cell lines, RAW 264.7 cells.
Products
-
Cat. No.Product NameDescriptionTargetResearch Area
-