2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid
Based on 1 Customer Validation
2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid, a natural ursane-type triterpene, is a potent inhibitor of HIV protease (HIV Protease). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid is also an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid displays an inhibitory activity against nitric oxide production in Lipopolysaccharide (Lipopolysaccharides)-activated RAW 264.7 cells.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 176983-21-4
- Formula: C30H46O5
- Molecular Weight:486.68
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid (0.01-0.1 μM) displays moderate inhibitory activities against nitric oxide production in Lipopolysaccharide-activated macrophage cell lines, RAW 264.7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female ICR mice (6 weeks old)[2]
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Dosage:0.0025%
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Administration:Drinking water; for 20 weeks
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Result:Showed an inhibitory effect on the activation of EBV-EA induced by 12-O-tetradecanoylphorbol-13-acetate (TPA).
Chemical Information
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CAS No. 176983-21-4
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Appearance Solid
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Molecular Weight 486.68
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Formula C30H46O5
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Color White to off-white
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SMILES
OC([C@]12[C@]([C@](O)([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)(C([C@@H](C4)O)=O)C)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid Related Classifications
HY-N4155 Related Classifications
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