177847-28-8
177847-28-8
Chemical Structure
UR-7247
- CAS No.: 177847-28-8
- Formula:C24H26N6O2
- Molecular Weight:430.50
IUPAC Name: 5-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-3-isopropyl-1-propyl-1H-pyrazole-4-carboxylic acid
InChIKey: FOVKKLYIXHRZPA-UHFFFAOYSA-N
SMILES: O=C(O)C1=C(N(N=C1C(C)C)CCC)CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=NN4
Biological Activity: UR-7247 is a potent and orally active angiotensin II AT1 receptor antagonist. UR-7247 decreases arterial pressure and increases renal blood flow[1][2].
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UR-7247 | UR-7247 is a potent and orally active angiotensin II AT1 receptor antagonist. UR-7247 decreases arterial pressure and increases renal blood flow. | |||||||||||||||||||||
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References
- [1]. Maillard MP, et al. Pharmacologic profile of UR-7247, an orally active angiotensin II AT1 receptor antagonist, in healthy volunteers. p6. J Cardiovasc Pharmacol. 2000 Mar;35(3):383-9. [Content Brief]
- [2]. Alexander Scriabine, et al. New Cardiovascular Drugs, XIIIth International Congress of Pharmacology, Munich, Germany, July 26-31, 1998. 16(3):312-317.
Keywords
