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Cat. No.: HY-117805

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UR-7247

UR-7247 is a potent and orally active angiotensin II AT1 receptor antagonist. UR-7247 decreases arterial pressure and increases renal blood flow.

For research use only. We do not sell to patients.

CAS No.: 177847-28-8
Formula: C₂₄H₂₆N₆O₂
Molecular Weight:430.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

UR-7247 Chemical Structure

CAS No.: 177847-28-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

UR-7247 is a potent and orally active angiotensin II AT1 receptor antagonist. UR-7247 decreases arterial pressure and increases renal blood flow^[1]^[2].

IC₅₀ & Target^[1]

AT1 Receptor

All Angiotensin Receptor Isoforms :

Chemical Information

CAS No. 177847-28-8
Molecular Weight 430.50
Formula C₂₄H₂₆N₆O₂
SMILES

O=C(O)C1=C(N(N=C1C(C)C)CCC)CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=NN4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Maillard MP, et al. Pharmacologic profile of UR-7247, an orally active angiotensin II AT1 receptor antagonist, in healthy volunteers. p6. J Cardiovasc Pharmacol. 2000 Mar;35(3):383-9. [Content Brief]

[2]. Alexander Scriabine, et al. New Cardiovascular Drugs, XIIIth International Congress of Pharmacology, Munich, Germany, July 26-31, 1998. 16(3):312-317.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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UR-7247

All Angiotensin Receptor Isoforms