178451-13-3
Chemical Structure
Raloxifene 6-Monomethyl Ether
- CAS No.: 178451-13-3
- Formula:C29H29NO4S
- Molecular Weight:487.61
IUPAC Name: (2-(4-hydroxyphenyl)-6-methoxybenzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone
InChIKey: KOFDGHCTXVZHIH-UHFFFAOYSA-N
SMILES: O=C(C1=C(C2=CC=C(O)C=C2)SC3=CC(OC)=CC=C31)C4=CC=C(OCCN5CCCCC5)C=C4
Biological Activity: Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 250 nM and a pIC50 of 6.6[1].
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Raloxifene 6-Monomethyl Ether | Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 250 nM and a pIC50 of 6.6. | |||||||||||||||||||||
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Keywords