1794756-15-2
1794756-15-2
Chemical Structure
Amisulpride-d5 N-Oxide
- CAS No.: 1794756-15-2
- Formula:C17H22D5N3O5S
- Molecular Weight:390.51
IUPAC Name: 2-((4-amino-5-(ethylsulfonyl)-2-methoxybenzamido)methyl)-1-(ethyl-d5)pyrrolidine 1-oxide
InChIKey: LLIKIPAUZJTRGB-SGEUAGPISA-N
SMILES: [2H]C([2H])([2H])C([2H])([2H])N(C1CNC(C2=C(C=C(C(S(CC)(=O)=O)=C2)N)OC)=O)(CCC1)=O
Biological Activity: Amisulpride-d5 N-Oxide is the deuterium labeled Amisulpride. Amisulpride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Amisulpride-d5 N-Oxide | Amisulpride-d5 N-Oxide is the deuterium labeled Amisulpride. Amisulpride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Amisulpride N-oxide | Amisulpride N-oxide is a photodegradation product of Amisulpride (HY-14545) (a dopamine D2/D3 receptor antagonist). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Schoemaker H, et al. Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity. J Pharmacol Exp Ther. 1997 Jan;280(1):83-97. [Content Brief]
