1794942-12-3
1794942-12-3
Chemical Structure
Maprotiline-d5 hydrochloride
- CAS No.: 1794942-12-3
- Formula:C20H19D5ClN
- Molecular Weight:318.90
IUPAC Name: 3-(9,10-ethanoanthracen-9(10H)-yl)-N-(methyl-d3)propan-1,1-d2-1-amine hydrochloride
InChIKey: NZDMFGKECODQRY-QHZJUOFTSA-N
SMILES: C(CC(NC([2H])([2H])[2H])([2H])[2H])C12C=3C(C(C=4C1=CC=CC4)CC2)=CC=CC3.Cl
Biological Activity: Maprotiline-d5 (hydrochloride) is the deuterium labeled Maprotiline hydrochloride. Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant[1][2].
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Maprotiline-d5 hydrochloride | Maprotiline-d5 (hydrochloride) is the deuterium labeled Maprotiline hydrochloride. Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant. | |||||||||||||||||||||
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Maprotiline hydrochloride (Standard) | 99.99% | Maprotiline (hydrochloride) (Standard) is the analytical standard of Maprotiline (hydrochloride). Maprotiline (hydrochloride) (Standard) is a highly selective noradrenergic reuptake inhibitor that has strong antidepressant, antitumor and neuropathic pain-relieving effects. Maprotiline (hydrochloride) (Standard) induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1. | ||||||||||||||||||||
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Maprotiline-d3 hydrochloride | 98.80% | Maprotiline-d3 (hydrochloride) is deuterium labeled Maprotiline (hydrochloride). | ||||||||||||||||||||
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Maprotiline hydrochloride | 99.84% | Maprotiline hydrochloride is a highly selective noradrenergic reuptake inhibitor that has strong antidepressant, antitumor and neuropathic pain-relieving effects with oral activity. Maprotiline hydrochloride induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Peng, W.H., et al., Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice. Life Sci, 2007. 81(11): p. 933-8. [Content Brief]
