Maprotiline-d3 hydrochloride
Based on 1 Customer Validation
Maprotiline-d3 (hydrochloride) is deuterium labeled Maprotiline (hydrochloride).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.80%
- No. CAS: 1329496-63-0
- Fòrmula: C20H21D3ClN
- Peso molecular:316.88
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 1329496-63-0
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Unlabeled Cas 10347-81-6
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Appearance Solid
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Peso molecular 316.88
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Fòrmula C20H21D3ClN
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Color White to off-white
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SMILES
[2H]C([2H])([2H])NCCCC12C3=CC=CC=C3C(CC2)C4=CC=CC=C41.Cl
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 83.33 mg/mL (262.97 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 2.2 mg/mL (6.94 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Peng, W.H., et al., Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice. Life Sci, 2007. 81(11): p. 933-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 3.1558 mL | 15.7788 mL | 31.5577 mL | 78.8942 mL |
| 5 mM | 0.6312 mL | 3.1558 mL | 6.3115 mL | 15.7788 mL | |
| DMSO | 10 mM | 0.3156 mL | 1.5779 mL | 3.1558 mL | 7.8894 mL |
| 15 mM | 0.2104 mL | 1.0519 mL | 2.1038 mL | 5.2596 mL | |
| 20 mM | 0.1578 mL | 0.7889 mL | 1.5779 mL | 3.9447 mL | |
| 25 mM | 0.1262 mL | 0.6312 mL | 1.2623 mL | 3.1558 mL | |
| 30 mM | 0.1052 mL | 0.5260 mL | 1.0519 mL | 2.6298 mL | |
| 40 mM | 0.0789 mL | 0.3945 mL | 0.7889 mL | 1.9724 mL | |
| 50 mM | 0.0631 mL | 0.3156 mL | 0.6312 mL | 1.5779 mL | |
| 60 mM | 0.0526 mL | 0.2630 mL | 0.5260 mL | 1.3149 mL | |
| 80 mM | 0.0394 mL | 0.1972 mL | 0.3945 mL | 0.9862 mL | |
| 100 mM | 0.0316 mL | 0.1578 mL | 0.3156 mL | 0.7889 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Maprotiline-d3 hydrochloride Related Classifications
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