180300-52-1
Chemical Structure
3’-β-C-Ethynyl-5-methyl uridine
- CAS No.: 180300-52-1
- Formula:C12H14N2O6
- Molecular Weight:282.25
IUPAC Name: 1-((2R,3R,4S,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: GVFXQDTVLQIXNR-UJYYTQATSA-N
SMILES: OC[C@@H]1[C@](O)(C#C)[C@@H](O)[C@H](N(C(N2)=O)C=C(C)C2=O)O1
Biological Activity: 3’-β-C-Ethynyl-5-methyl uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. 3’-β-C-Ethynyl-5-methyl uridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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3’-β-C-Ethynyl-5-methyl uridine | 3’-β-C-Ethynyl-5-methyl uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis. 3’-β-C-Ethynyl-5-methyl uridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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Keywords
