3’-β-C-Ethynyl-5-methyl uridine
3’-β-C-Ethynyl-5-methyl uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis. 3’-β-C-Ethynyl-5-methyl uridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- CAS No.: 180300-52-1
- Formula: C12H14N2O6
- Molecular Weight:282.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| KB | IC50 |
>300 μM
Compound: EMUrd(14c)
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In vitro tumor cell growth inhibitory activity against human nasopharyngeal KB cell lines
In vitro tumor cell growth inhibitory activity against human nasopharyngeal KB cell lines
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[PMID: 8960561] |
| L1210 | IC50 |
>300 μM
Compound: EMUrd(14c)
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In vitro tumor cell growth inhibitory activity against mouse leukemia L1210 cell lines.
In vitro tumor cell growth inhibitory activity against mouse leukemia L1210 cell lines.
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[PMID: 8960561] |
Chemical Information
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CAS No. 180300-52-1
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Molecular Weight 282.25
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Formula C12H14N2O6
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SMILES
OC[C@@H]1[C@](O)(C#C)[C@@H](O)[C@H](N(C(N2)=O)C=C(C)C2=O)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
3’-β-C-Ethynyl-5-methyl uridine Related Classifications
HY-152488 Related Classifications
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