1809163-24-3
1809163-24-3
Chemical Structure
HDAC-IN-43
- CAS No.: 1809163-24-3
- Formula:C22H28N6O4
- Molecular Weight:440.50
IUPAC Name: N-hydroxy-4-(3-(9-isopropyl-2-morpholino-9H-purin-6-yl)phenoxy)butanamide
InChIKey: JSFJWFPAULATEH-UHFFFAOYSA-N
SMILES: O=C(NO)CCCOC1=CC=CC(C2=C3N=CN(C(C)C)C3=NC(N4CCOCC4)=N2)=C1
Biological Activity: HDAC-IN-43 is a potent HDAC 1/3/6 inhibitor with IC50 values of 82, 45, and 24 nM, respectively. HDAC-IN-43 is a weak PI3K/mTOR inhibitors with IC50 values of 3.6 and 3.7 μM, respectively. HDAC-IN-43 shows broad anti-proliferative activity [1].
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HDAC-IN-43 | HDAC-IN-43 is a potent HDAC 1/3/6 inhibitor with IC50 values of 82, 45, and 24 nM, respectively. HDAC-IN-43 is a weak PI3K/mTOR inhibitors with IC50 values of 3.6 and 3.7 μM, respectively. HDAC-IN-43 shows broad anti-proliferative activity . | |||||||||||||||||||||
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References
Keywords
