1822810-13-8
1822810-13-8
Chemical Structure
Monomethyl auristatin E intermediate-5
- CAS No.: 1822810-13-8
- Formula:C19H27NO5
- Molecular Weight:349.42
IUPAC Name: tert-butyl 4-(((benzyloxy)carbonyl)amino)-5-methyl-3-oxohexanoate
InChIKey: FGKFTCDIARXOCS-UHFFFAOYSA-N
SMILES: CC(C(NC(OCC1=CC=CC=C1)=O)C(CC(OC(C)(C)C)=O)=O)C
Biological Activity: Monomethyl auristatin E intermediate-5 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
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Monomethyl auristatin E intermediate-5 | Monomethyl auristatin E intermediate-5 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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