1838622-25-5
1838622-25-5
Chemical Structure
EST73502
- CAS No.: 1838622-25-5
- Formula:C19H26F2N2O2
- Molecular Weight:352.42
IUPAC Name: (R)-9-(2,5-difluorophenethyl)-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
InChIKey: KALIKXMQWFLZKB-CQSZACIVSA-N
SMILES: FC1=CC=C(F)C=C1CCN(CC2)CCC2(O[C@@H]3C)CN(CC)C3=O
Biological Activity: EST73502 is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with Kis of 64 nM and 118 nM for MOR and σ1R, respectively. EST73502 has antinociceptive activity[1].
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EST73502 | EST73502 is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with Kis of 64 nM and 118 nM for MOR and σ1R, respectively. EST73502 has antinociceptive activity. | |||||||||||||||||||||
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References
Keywords
