1863967-01-4
1863967-01-4
Chemical Structure
MCL-524
- CAS No.: 1863967-01-4
- Formula:C21H24FNO3
- Molecular Weight:357.42
InChIKey: BVBIAGFWBHXIBM-QGZVFWFLSA-N
SMILES: OC1=CC=C2C(C3=C4C(CCN(CCC)[C@]4([H])C2)=CC(OCCF)=C3)=C1O
Biological Activity: MCL-524 is a highly selective full agonist of the dopamine D2 receptor with a Kd value of 1.34 nM. MCL-524 specifically binds to the high-affinity state of the dopamine D2 receptor; this binding is abolished by guanylylimidodiphosphate, and it can distinguish between D2high and D2low sites. MCL-524 is applicable to research related to Parkinson's disease and schizophrenia[1].
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MCL-524 | MCL-524 is a highly selective full agonist of the dopamine D2 receptor with a Kd value of 1.34 nM. MCL-524 specifically binds to the high-affinity state of the dopamine D2 receptor; this binding is abolished by guanylylimidodiphosphate, and it can distinguish between D2high and D2low sites. MCL-524 is applicable to research related to Parkinson's disease and schizophrenia. | |||||||||||||||||||||
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References
Keywords
