187585-11-1
187585-11-1
Chemical Structure
DD1
- CAS No.: 187585-11-1
- Formula:C16H14N2O3
- Molecular Weight:282.29
IUPAC Name: 3-amino-2-(3-amino-4-methoxyphenyl)-4H-chromen-4-one
InChIKey: HSRUZXHIEFFBHR-UHFFFAOYSA-N
SMILES: O=C1C(N)=C(C2=CC=C(OC)C(N)=C2)OC3=CC=CC=C13
Biological Activity: DD1, a proteasome inhibitor, targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis. DD1 induces apoptosis in the caspase-dependent manner. DD1 induces mitochondrial membrane depolarization and Bad dephosphorylation[1].
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DD1 | 99.40% | DD1, a proteasome inhibitor, targets Bax activation and P70S6K degradation during acute myeloid leukemia (AML) apoptosis. DD1 induces apoptosis in the caspase-dependent manner. DD1 induces mitochondrial membrane depolarization and Bad dephosphorylation. | ||||||||||||||||||||
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References
Keywords
