190581-71-6
190581-71-6
Chemical Structure
(R)-Lanicemine
Synonym(s): (R)-AZD6765
- CAS. Nr.: 190581-71-6
- Formula:C13H14N2
- Molecular Weight:198.26
IUPAC Name: (R)-1-phenyl-2-(pyridin-2-yl)ethan-1-amine
InChIKey: FWUQWDCOOWEXRY-CYBMUJFWSA-N
SMILES: N[C@@H](C1=CC=CC=C1)CC2=CC=CC=N2
Biological Activity: (R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects[1].
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(R)-Lanicemine | (R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects. | |||||||||||||||||||||
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(R)-Lanicemine-d5 | (R)-Lanicemine-d5 ((R)-AZd6765-d5) is the deuterium labeled (R)-Lanicemine (HY-108235C). (R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1?μM for NMDA receptor; IC50s of 4-7?μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects. | |||||||||||||||||||||
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References
Keywords
