1936442-71-5
1936442-71-5
Chemical Structure
IDP-73152 mesylate
- CAS No.: 1936442-71-5
- Formula:C29H45F3N4O7S
- Molecular Weight:650.75
InChIKey: AURIORGFGUWJMG-RGFBGPCLSA-N
SMILES: CS(=O)(O)=O.O=C(N1CCC(CC1)NCC2=C(C=C(C(F)=C2)F)F)[C@H](C(C)(C)C)NC([C@@H](CN(O)C=O)CC3CCCC3)=O
Biological Activity: IDP-73152 mesylate is an orally active bacterial Peptide deformylase inhibitor and Antibiotic. IDP-73152 mesylate exhibits activity against Gram-positive bacteria. IDP-73152 mesylate can be used in the research of infections caused by Streptococcus pneumoniae, Enterococcus faecium and Staphylococcus aureus[1][2][3].
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IDP-73152 mesylate | IDP-73152 mesylate is an orally active bacterial Peptide deformylase inhibitor and Antibiotic. IDP-73152 mesylate exhibits activity against Gram-positive bacteria. IDP-73152 mesylate can be used in the research of infections caused by Streptococcus pneumoniae, Enterococcus faecium and Staphylococcus aureus. | |||||||||||||||||||||
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References
- [1]. Lee M, et al. Quantification of IDP-73152, a novel antibiotic, in plasma from mice, rats and humans using an ultra-high performance liquid chromatography/tandem mass spectrometry method for use in pharmacokinetic studies. Journal of pharmaceutical and biomedical analysis. 2017 Oct 25;145:364-371.
- [2]. 이명재. Physiologically-based pharmacokinetic modeling of a novel antibacterial drug (IDP-73152) for prediction of its pharmacokinetics in humans[D]. 서울대학교 대학원, 2022.
- [3]. Lee M, et al. Prediction of Pharmacokinetics of IDP-73152 in Humans Using Physiologically-Based Pharmacokinetics. Pharmaceutics. 2022 May 28;14(6):1157.
