1957235-51-6
1957235-51-6
Chemical Structure
5-(2-Chloroacetamide) thalidomide
- CAS 番号: 1957235-51-6
- Formula:C15H12ClN3O5
- Molecular Weight:349.73
IUPAC Name: 2-chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)acetamide
InChIKey: OIDIVJNMVBHPAC-UHFFFAOYSA-N
SMILES: ClCC(NC1=CC=C2C(N(C(C2=C1)=O)C3CCC(NC3=O)=O)=O)=O
Biological Activity: 5-(2-Chloroacetamide) thalidomide is a Thalidomide (HY-14658) analogue. Thalidomide recruits E3 Ligase for the ubiquitinylation and subsequent destruction of a given protein. This structure features a chloroacetamide, which is a thiol-specific reactive group.
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5-(2-Chloroacetamide) thalidomide | 95.0% | 5-(2-Chloroacetamide) thalidomide is a Thalidomide (HY-14658) analogue. Thalidomide recruits E3 Ligase for the ubiquitinylation and subsequent destruction of a given protein. This structure features a chloroacetamide, which is a thiol-specific reactive group. | ||||||||||||||||||||
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Keywords
