1964517-04-1
Chemical Structure
NCATS-SM1441
- CAS No.: 1964517-04-1
- Formula:C31H25FN4O4S3
- Molecular Weight:632.75
IUPAC Name: 2-(5-(cyclopropylmethyl)-4-(3-fluoro-4-sulfamoylbenzyl)-3-(3-((5-methylthiophen-2-yl)ethynyl)phenyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid
InChIKey: LZIKVHXLVMNROK-UHFFFAOYSA-N
SMILES: O=C(C1=CSC(N2N=C(C(CC3=CC=C(S(=O)(N)=O)C(F)=C3)=C2CC4CC4)C5=CC(C#CC6=CC=C(C)S6)=CC=C5)=N1)O
Biological Activity: NCATS-SM1441 (compound 52) is a lactate dehydrogenase (LDH) inhibitor (IC50=40 nM). By inhibiting the activity of LDH, NCATS-SM1441 is able to reduce the production of lactic acid in cancer cells, helping to slow or stop the proliferation of cancer cells. NCATS-SM1441 can be used to study cancer metabolism[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NCATS-SM1441 | 98.65% | NCATS-SM1441 (compound 52) is a lactate dehydrogenase (LDH) inhibitor (IC50=40 nM). By inhibiting the activity of LDH, NCATS-SM1441 is able to reduce the production of lactic acid in cancer cells, helping to slow or stop the proliferation of cancer cells. NCATS-SM1441 can be used to study cancer metabolism. | ||||||||||||||||||||
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Keywords
