20188-85-6
Chemical Structure
Ombuoside
- CAS 番号: 20188-85-6
- Formula:C29H34O16
- Molecular Weight:638.57
IUPAC Name: 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
InChIKey: VVSFMIXQNYRGMG-BDAFLREQSA-N
SMILES: O=C1C(O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]([C@H]2O)CO[C@H](O[C@H]3C)[C@@H]([C@@H]([C@H]3O)O)O)=C(C(C=C4)=CC(O)=C4OC)OC5=CC(OC)=CC(O)=C15
Biological Activity: Ombuoside has antioxidant properties, inhibiting ROS production and apoptosis. Ombuoside exerts neuroprotective effects through the ERK-JNK-caspase-3 system. Ombuoside promotes Dopamine biosynthesis through TH and CREB activation. Ombuoside exhibits antimicrobial activity against several Gram-positive and Gram-negative bacteria, as well as Candida albicans[1][2][3][4][5]
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Ombuoside | 99.68% | Ombuoside has antioxidant properties, inhibiting ROS production and apoptosis. Ombuoside exerts neuroprotective effects through the ERK-JNK-caspase-3 system. Ombuoside promotes Dopamine biosynthesis through TH and CREB activation. Ombuoside exhibits antimicrobial activity against several Gram-positive and Gram-negative bacteria, as well as Candida albicans | ||||||||||||||||||||
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References
- [1]. Wu X, et al. New application of ombuoside in protecting auditory cells from cisplatin-induced ototoxicity via the apoptosis pathway. Heliyon. 2024 Oct 9;10(20):e39166. [Content Brief]
- [2]. Davaasambuu U, et al.Ombuoside from Gynostemma pentaphyllum Protects PC12 Cells from L-DOPA-Induced Neurotoxicity. Planta Med. 2018 Sep;84(14):1007-1012. [Content Brief]
- [3]. Uchralsaikhan Davaasambuu1, et al. Ameliorative Effects of Ombuoside on Dopamine Biosynthesis in PC12 Cells. Natural Product Sciences 2018;24(2):99-102.
- [4]. Amaro-Luis JM, et al. Isolation, identification and antimicrobial activity of ombuoside from Stevia triflora. Ann Pharm Fr. 1997;55(6):262-8. [Content Brief]
- [5]. Abreu PM, et al. Antioxidant compounds from Ebenus pinnata. Fitoterapia. 2007 Jan;78(1):32-4. [Content Brief]
