20410-87-1
20410-87-1
Chemical Structure
Anabasamine
- CAS No.: 20410-87-1
- Formula:C16H19N3
- Molecular Weight:253.34
IUPAC Name: 5-(1-methylpiperidin-2-yl)-2,3'-bipyridine
InChIKey: TZRDBHMKTWECOV-UHFFFAOYSA-N
SMILES: CN1C(C2=CN=C(C3=CN=CC=C3)C=C2)CCCC1
Biological Activity: Anabasamine is an alkaloid. Anabasamine can be isolated from the aerial parts of Anabasis aphylla L. As an inhibitor of Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE), Anabasamine has a pKi value of 3.49 against AChE and 2.08 against BuChE[1][2][3].
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Anabasamine | Anabasamine is an alkaloid. Anabasamine can be isolated from the aerial parts of Anabasis aphylla L. As an inhibitor of Acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE), Anabasamine has a pKi value of 3.49 against AChE and 2.08 against BuChE. | |||||||||||||||||||||
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References
- [1]. Tilyabaev Z, et al. Alkaloids of Anabasis aphylla and their cholinergic activities[J]. Chemistry of natural compounds, 1998, 34(3): 295-297.
- [2]. Bala I A, et al. Synthesis, antimicrobial, cytotoxic and in silico studies of pyridine-quinazolin-4 (3H)-one hybrids[J]. Journal of Molecular Structure, 2025, 1338: 142275.
- [3]. Du H, et al. Alkaloids from Anabasis aphylla L. J Asian Nat Prod Res. 2008 Nov-Dec;10(11-12):1093-5.
Keywords
