2072145-29-8
2072145-29-8
Chemical Structure
2’-Deoxy-2’-fluoro-alpha-D-arabinoguanosine
- CAS No.: 2072145-29-8
- Formula:C10H12FN5O4
- Molecular Weight:285.23
IUPAC Name: 2-amino-9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one
InChIKey: UXUZARPLRQRNNX-DXTOWSMRSA-N
SMILES: OC[C@@H]1[C@@H](O)[C@@H](F)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O1
Biological Activity: 2’-Deoxy-2’-fluoro-alpha-D-arabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-2’-fluoro-alpha-D-arabinoguanosine | 2’-Deoxy-2’-fluoro-alpha-D-arabinoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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