2089130-74-3
Chemical Structure
LEO 134310
- CAS No.: 2089130-74-3
- Formula:C34H40N2O8
- Molecular Weight:604.69
IUPAC Name: (S)-1-((R)-5-oxotetrahydrofuran-3-carbonyl)piperidin-3-yl 4-((1R,2S)-1-(4-cyclopropylphenyl)-2-((R)-tetrahydrofuran-2-carboxamido)propoxy)benzoate
InChIKey: NADMBBGHEQYUMJ-WDXNIXBWSA-N
SMILES: O=C([C@@H]1CC(OC1)=O)N(CCC2)C[C@H]2OC(C(C=C3)=CC=C3O[C@H](C4=CC=C(C5CC5)C=C4)[C@H](C)NC([C@H]6CCCO6)=O)=O
Biological Activity: LEO 134310 is a selective, non-steroidal glucocorticoid receptor (GR) agonist optimized for topical research., LEO 134310 showed high affinity (EC50 of 14 nM) in a GR binding assay. LEO 134310 can be used for skin diseases[1].
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LEO 134310 | LEO 134310 is a selective, non-steroidal glucocorticoid receptor (GR) agonist optimized for topical research., LEO 134310 showed high affinity (EC50 of 14 nM) in a GR binding assay. LEO 134310 can be used for skin diseases. | |||||||||||||||||||||
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Keywords
