LEO 134310
LEO 134310 is a selective, non-steroidal glucocorticoid receptor (GR) agonist optimized for topical research., LEO 134310 showed high affinity (EC50 of 14 nM) in a GR binding assay. LEO 134310 can be used for skin diseases.
For research use only. We do not sell to patients.
- CAS No.: 2089130-74-3
- Formula: C34H40N2O8
- Molecular Weight:604.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2089130-74-3
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Molecular Weight 604.69
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Formula C34H40N2O8
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SMILES
O=C([C@@H]1CC(OC1)=O)N(CCC2)C[C@H]2OC(C(C=C3)=CC=C3O[C@H](C4=CC=C(C5CC5)C=C4)[C@H](C)NC([C@H]6CCCO6)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)