2102694-52-8
Chemical Structure
PROTAC Her3 Degrader-1
- CAS No.: 2102694-52-8
- Formula:C50H57Cl2N9O13
- Molecular Weight:1062.95
IUPAC Name: 2-(4-(3-((3-cyano-4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinolin-7-yl)oxy)propyl)piperazin-1-yl)-N-(1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)-2-oxo-6,9,12-trioxa-3-azatetradecan-14-yl)acetamide
InChIKey: DJKVWYHMRCECLZ-UHFFFAOYSA-N
SMILES: N#CC1=CN=C2C=C(C(OC)=CC2=C1NC3=CC(OC)=C(C=C3Cl)Cl)OCCCN4CCN(CC4)CC(NCCOCCOCCOCCNC(COC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=O)=O
Biological Activity: PROTAC Her3 Degrader-1 (compound CY1) is a Her3 PROTAC degrader that recruits CRBN. PROTAC Her3 Degrader-1 is applicable to research related to breast cancer, lung cancer, head and neck cancer, and prostate cancer[1].
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PROTAC Her3 Degrader-1 | PROTAC Her3 Degrader-1 (compound CY1) is a Her3 PROTAC degrader that recruits CRBN. PROTAC Her3 Degrader-1 is applicable to research related to breast cancer, lung cancer, head and neck cancer, and prostate cancer. | |||||||||||||||||||||
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