PROTAC Her3 Degrader-1
PROTAC Her3 Degrader-1 (compound CY1) is a Her3 PROTAC degrader that recruits CRBN. PROTAC Her3 Degrader-1 is applicable to research related to breast cancer, lung cancer, head and neck cancer, and prostate cancer.
For research use only. We do not sell to patients.
- CAS No.: 2102694-52-8
- Formula: C50H57Cl2N9O13
- Molecular Weight:1062.95
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
HER3 |
Chemical Information
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CAS No. 2102694-52-8
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Molecular Weight 1062.95
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Formula C50H57Cl2N9O13
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SMILES
N#CC1=CN=C2C=C(C(OC)=CC2=C1NC3=CC(OC)=C(C=C3Cl)Cl)OCCCN4CCN(CC4)CC(NCCOCCOCCOCCNC(COC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)