2143956-20-9
2143956-20-9
Chemical Structure
PROTAC RIPK2 Degrader-1
- CAS No.: 2143956-20-9
- Formula:C53H65FN14O7S2
- Molecular Weight:1093.30
IUPAC Name: 3-(4-bromophenyl)pyrrolidin-2-one
InChIKey: HZMQXNZSFFXKMT-LCPJFFRWSA-N
SMILES: O=C(N1CCC(CC1)[C@H](NC([C@H](C)NC)=O)C(N2[C@@](C3=NC(C(C4=CC=C(C=C4)F)=O)=CS3)([H])CCC2)=O)C5=CN=C(N=C5)N(CC6)CCN6CCOC(C(S(C(C)(C)C)(=O)=O)=C7)=CC8=C7C(NC9=NNC(C)=C9C)=NC=N8
Biological Activity: RIPK2-IN-2 (example 25) is a RIP2 kinase PROTAC inhibitor. RIPK2-IN-2 can block RIP2-dependent proinflammatory signaling, regulated RIP2 kinase activity in auto inflammatory diseases[1].
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PROTAC RIPK2 Degrader-1 | RIPK2-IN-2 (example 25) is a RIP2 kinase PROTAC inhibitor. RIPK2-IN-2 can block RIP2-dependent proinflammatory signaling, regulated RIP2 kinase activity in auto inflammatory diseases. | |||||||||||||||||||||
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References
Keywords
