215123-80-1
215123-80-1
Chemical Structure
SD 8381
- CAS No.: 215123-80-1
- Formula:C11H5Cl2F3O3
- Molecular Weight:313.06
IUPAC Name: (S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
InChIKey: ZFKBWSREWJOSSJ-VIFPVBQESA-N
SMILES: ClC1=C2C(C=C([C@H](O2)C(F)(F)F)C(O)=O)=CC(Cl)=C1
Biological Activity: SD 8381 is a potent and selective COX-2 inhibitor. SD 8381 shows IC50 values of 0.0098 μM for hCOX-2 and 0.69 μM for hCOX-1[1].
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SD 8381 | SD 8381 is a potent and selective COX-2 inhibitor. SD 8381 shows IC50 values of 0.0098 μM for hCOX-2 and 0.69 μM for hCOX-1. | |||||||||||||||||||||
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Keywords
