2155851-88-8
2155851-88-8
Chemical Structure
Axatilimab
Synonym(s): SNDX-6352
- CAS No.: 2155851-88-8
- Formula:N/A
- Molecular Weight:(147.18 kDa)
IUPAC Name: 2-(2-fluoro-5-methoxyphenyl)ethan-1-amine hydrochloride
SMILES: [Axatilimab]
Biological Activity: Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Axatilimab | 99.59% | Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases. | ||||||||||||||||||||
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References
- [1]. Arora M, et al. Phase 1 study of axatilimab (SNDX-6352), a CSF-1R humanized antibody, for chronic graft-versus-host disease after 2 or more lines of systemic treatment. Blood, 2020, 136: 1-2.
- [2]. Tiessen R, et al. First in human, single ascending dose study in healthy volunteers of SNDX-6352, a humanized IgG4 monoclonal antibody targeting colony stimulating factor-1 receptor (CSF-1R). J Immunother Cancer, 2016, 5: P505.
Keywords
