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  3. Axatilimab

Axatilimab  (Synonyms: SNDX-6352)

Cat. No.: HY-P99452 Purity: 99.59%
COA

Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases.

For research use only. We do not sell to patients.

Axatilimab Chemical Structure

Axatilimab Chemical Structure

CAS No. : 2155851-88-8

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1 mg USD 300 In-stock
5 mg USD 780 In-stock
10 mg USD 1250 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases[1][2].

Isotype

Human IgG4 kappa

Recommend Isotype Controls
Species

Humanized

In Vitro

Axatilimab (SNDX-6352) affects the migration, proliferation, differentiation, and survival of monocytes and macrophages by binding to CSF-1R and blocking its activation by its two known ligands, CSF-1 and IL-34[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Axatilimab]

Shipping

Shipping with dry ice.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Axatilimab Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Axatilimab
Cat. No.:
HY-P99452
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