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Axatilimab

(Synonyms: SNDX-6352)
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Based on 1 Customer Validation

Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases.

For research use only. We do not sell to patients.

  • Purity: 99.59%
  • CAS No.: 2155851-88-8
  • Molecular Weight:147.18 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Axatilimab
  • Experimental Validation Results for Axatilimab
  • Experimental Validation Results for Axatilimab
  • Axatilimab Chemical Structure
    Axatilimab Chemical Structure
CAS No.: 2155851-88-8
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Loaded CSF1R Protein, Human (HEK293, His-Fc, HY-P75323) on HIS1K biosensor, can bind Axatilimab with an affinity constant of 1.467E-11 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1.5X106 THP-1 cells labeling Axatilimab (HY-P99452, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Cells without incubation with primary antibody were used as the unlabeled control (black).

  • Axatilimab Chemical Structure
    1/16
  • Axatilimab
  • Loaded CSF1R Protein, Human (HEK293, His-Fc, HY-P75323) on HIS1K biosensor, can bind Axatilimab with an affinity constant of 1.467E-11 M as determined in BLI assay.
  • Flow cytometric analysis of 1.5X106 THP-1 cells labeling Axatilimab (HY-P99452, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Cells without incubation with primary antibody were used as the unlabeled control (black).