2. Protein Tyrosine Kinase/RTK
  3. c-Fms
  4. Axatilimab

Axatilimab  (Synonyms: SNDX-6352)

Cat. No.: HY-P99452 Purity: 99.59%
COA

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Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases.

For research use only. We do not sell to patients.

Axatilimab Chemical Structure

Axatilimab Chemical Structure

CAS No. : 2155851-88-8

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1 mg USD 300 In-stock
5 mg USD 780 In-stock
10 mg USD 1250 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Axatilimab Related Antibodies

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Description

Axatilimab (SNDX-6352) is a humanized IgG4 antibody with high affinity to CSF-1R. Axatilimab can be used for the research of chronic graft versus host disease (cGVHD) and neoplastic diseases[1][2].

In Vitro

Axatilimab (SNDX-6352) affects the migration, proliferation, differentiation, and survival of monocytes and macrophages by binding to CSF-1R and blocking its activation by its two known ligands, CSF-1 and IL-34[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Axatilimab Related Antibodies
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Axatilimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 99.59%

COA (231 KB)

Handling Instructions (2659 KB)
References
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Axatilimab Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Axatilimab2155851-88-8SNDX-6352SNDX6352SNDX 6352c-FmsCSF-1 receptorcolony stimulating factor 1 receptorCSF-1RCSF1Rchronic graft versus host diseasecGVHDneoplastic diseasesInhibitorinhibitorinhibit

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