2157482-40-9
2157482-40-9
Chemical Structure
FGFR1 inhibitor-11
- CAS No.: 2157482-40-9
- Formula:C23H18O4
- Molecular Weight:358.39
InChIKey: MQULDLLQOGCFOW-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C2=C(C(C3=CC=CC=C3O2)=O)CC4=C(C=CC=C4)O
Biological Activity: FGFR1 inhibitor-11 (compound 5g) binds to FGFR1, inactivation of its downstream ERK1/2 and IκBα/NF-κB signaling inhibited RANKL-induced osteoclastogenesis. FGFR1 inhibitor-11 has oral bioactivity[1].
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FGFR1 inhibitor-11 | FGFR1 inhibitor-11 (compound 5g) binds to FGFR1, inactivation of its downstream ERK1/2 and IκBα/NF-κB signaling inhibited RANKL-induced osteoclastogenesis. FGFR1 inhibitor-11 has oral bioactivity. | |||||||||||||||||||||
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References
Keywords
