2163782-59-8
Chemical Structure
Pralurbactam
Synonym(s): FL058
- CAS No.: 2163782-59-8
- Formula:C10H18N6O8S
- Molecular Weight:382.35
IUPAC Name: (S)-2-(((tert-butyldiphenylsilyl)oxy)methyl)azetidine
InChIKey: HOJIPBUGHMYVQD-RQJHMYQMSA-N
SMILES: O=C([C@H](CC1)[N@@](C[C@]1([H])N2O[S](=O)(O)=O)C2=O)NOCCONC(N)=N
Biological Activity: Pralurbactam (FL058) is a β-lactamase (Beta-lactamase) inhibitor. Pralurbactam enhances the antibacterial activity of Imipenem against Mycobacterium abscessus. Pralurbactam reduces the pulmonary bacterial load in neutropenic mice infected with Mycobacterium abscessus. Pralurbactam can be used in research related to infections caused by Mycobacterium abscessus complex, Escherichia coli, and Klebsiella pneumoniae[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Pralurbactam | 98.69% | Pralurbactam (FL058) is a β-lactamase (Beta-lactamase) inhibitor. Pralurbactam enhances the antibacterial activity of Imipenem against Mycobacterium abscessus. Pralurbactam reduces the pulmonary bacterial load in neutropenic mice infected with Mycobacterium abscessus. Pralurbactam can be used in research related to infections caused by Mycobacterium abscessus complex, Escherichia coli, and Klebsiella pneumoniae. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Tan Z, et al. FL058, a novel β-lactamase inhibitor, increases the anti-Mycobacterium abscessus activity of imipenem. Int J Antimicrob Agents. 2025;65(2):107414. [Content Brief]
- [2]. Huang Z, et al. Pharmacokinetic/pharma-codynamic study of pralurbactam (FL058) combined with meropenem in a neutropenic murine thigh infection model. Front Microbiol. 2024;15:1516979. Published 2024 Dec 17. [Content Brief]
Keywords
