2204291-78-9
2204291-78-9
Chemical Structure
BK50164
- CAS No.: 2204291-78-9
- Formula:C13H13ClFN5O7
- Molecular Weight:405.72
IUPAC Name: 2-(((2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)methoxy)malonic acid
InChIKey: DDBYNIDRHBNGHN-FQKKHWMFSA-N
SMILES: NC1=NC(Cl)=NC2=C1N=CN2[C@@H]3O[C@H](COC(C(O)=O)C(O)=O)[C@@H](O)[C@@H]3F
Biological Activity: BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 μM. BK50164 binds to CD99 with a KD value of 1.5 μM. BK50164 shows antiproliferative activity. BK50164 induced Apoptosis and cell cycle arrest at Sub-G1 phase[1].
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BK50164 | BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 μM. BK50164 binds to CD99 with a KD value of 1.5 μM. BK50164 shows antiproliferative activity. BK50164 induced Apoptosis and cell cycle arrest at Sub-G1 phase. | |||||||||||||||||||||
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References
Keywords
