222551-05-5
Chemical Structure
Adoprazine hydrochloride
Synonym(s): SLV313 hydrochloride
- CAS No.: 222551-05-5
- Formula:C24H25ClFN3O2
- Molecular Weight:441.93
IUPAC Name: 1-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-4-((5-(4-fluorophenyl)pyridin-3-yl)methyl)piperazine hydrochloride
InChIKey: PAPGPUNOWOEIPA-UHFFFAOYSA-N
SMILES: FC1=CC=C(C2=CN=CC(CN3CCN(C4=C5OCCOC5=CC=C4)CC3)=C2)C=C1.[H]Cl
Biological Activity: Adoprazine (SLV313) hydrochloride is a full 5-HT1A receptor agonist with a pEC50 of 9 at cloned h5-HT1A receptors. Adoprazine hydrochloride is a full D2 and D3 receptor antagonist with pA2s of 9.3 and 8.9 at hD2 and hD3 receptors, respectively. Adoprazine has the characteristics of atypical antipsychotics[1].
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Adoprazine hydrochloride | Adoprazine (SLV313) hydrochloride is a full 5-HT1A receptor agonist with a pEC50 of 9 at cloned h5-HT1A receptors. Adoprazine hydrochloride is a full D2 and D3 receptor antagonist with pA2s of 9.3 and 8.9 at hD2 and hD3 receptors, respectively. Adoprazine has the characteristics of atypical antipsychotics. | |||||||||||||||||||||
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Keywords