2226507-04-4
Chemical Structure
BDP9066
- CAS No.: 2226507-04-4
- Formula:C20H24N6
- Molecular Weight:348.44
IUPAC Name: (S)-8-(3-(pyrimidin-4-yl)-7H-pyrrolo[2,3-b]pyridin-4-yl)-1,8-diazaspiro[5.5]undecane
InChIKey: UELSMLDRSQFVHG-FQEVSTJZSA-N
SMILES: C12=C(N3CCC[C@@]4(CCCCN4)C3)C=CNC1=NC=C2C5=NC=NC=C5
Biological Activity: BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with an IC50 of 64 nM for MRCKβ in SCC12 cells, Ki values of 0.0136 nM and 0.0233 nM for MRCKα/β in house determinations, respectively. BDP9066 has therapeutic effect on skin cancer by reducing substrate phosphorylation.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BDP9066 | 98.18% | BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with an IC50 of 64 nM for MRCKβ in SCC12 cells, Ki values of 0.0136 nM and 0.0233 nM for MRCKα/β in house determinations, respectively. BDP9066 has therapeutic effect on skin cancer by reducing substrate phosphorylation. | ||||||||||||||||||||
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Keywords
