2232134-77-7
2232134-77-7
Chemical Structure
Encofosbuvir
- CAS No.: 2232134-77-7
- Formula:C30H42FN4O13PS
- Molecular Weight:748.71
InChIKey: GAHCKEWMXZYJAZ-MDVIYHGYSA-N
SMILES: O=C(C=CN1[C@H]2[C@@](F)(C)[C@H](O)[C@@H](CO[P@@](N[C@@H](C)C(OC(C)C)=O)(OC3=CC=CC=C3)=O)O2)N(COC([C@@H](NC(OC)=O)CCSC)=O)C1=O
Biological Activity: Encofosbuvir is the inhibitor for HCV NS5B polymerase that inhibits GT1b, GT2a and GT3a with EC50 of 102.4, 82.51 and 46.91 nM. Encofosbuvir inhibits HCV replication and can be used for reseearchs of hepatitis C in mammals[1].
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Encofosbuvir | Encofosbuvir is the inhibitor for HCV NS5B polymerase that inhibits GT1b, GT2a and GT3a with EC50 of 102.4, 82.51 and 46.91 nM. Encofosbuvir inhibits HCV replication and can be used for reseearchs of hepatitis C in mammals. | |||||||||||||||||||||
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References
Keywords
