2243355-51-1

4-PQBH Chemical Structure
2243355-51-1

Chemical Structure

4-PQBH

  • CAS No.: 2243355-51-1
  • Formula:C22H17N5O
  • Molecular Weight:367.40

IUPAC Name: (E)-N'-(pyridin-4-ylmethylene)-4-(quinolin-4-ylamino)benzohydrazide

InChIKey: AVTFCFMDUCRAQC-MFKUBSTISA-N

SMILES: O=C(N/N=C/C1=CC=NC=C1)C2=CC=C(NC3=CC=NC4=CC=CC=C34)C=C2

Biological Activity: 4-PQBH is a potent Nur77 binder (KD=1.17 μM). 4-PQBH extensively induces caspase-independent cytoplasmic vacuolization and paraptosis through Nur77-mediated ER stress and autophagy. 4-PQBH can be used for cancer research[1].

Cat. No. Product Name Purity Description Pricing
HY-115901
4-PQBH 99.14% 4-PQBH is a potent Nur77 binder (KD=1.17 μM). 4-PQBH extensively induces caspase-independent cytoplasmic vacuolization and paraptosis through Nur77-mediated ER stress and autophagy. 4-PQBH can be used for cancer research.
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