2243709-60-4
2243709-60-4
Chemical Structure
DW14800
- CAS No.: 2243709-60-4
- Formula:C31H36N4O3
- Molecular Weight:512.64
IUPAC Name: N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-2-(4-(dimethylamino)benzoyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide
InChIKey: MQBNHAAEDHNZCH-UHFFFAOYSA-N
SMILES: CN(C)C1=CC=C(C(N2CCC(C=C(C(NCC(O)CN3CC(C=CC=C4)=C4CC3)=O)C=C5)=C5C2)=O)C=C1
Biological Activity: DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 17 nM. DW14800 reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. Anti-cancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DW14800 | 98.44% | DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 17 nM. DW14800 reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. Anti-cancer activity. | ||||||||||||||||||||
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References
Keywords
