1. Epigenetics
  2. Histone Methyltransferase
  3. DW14800

DW14800 

Cat. No.: HY-128579
Handling Instructions

DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 17 nM. DW14800 reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. Anti-cancer activity.

For research use only. We do not sell to patients.

DW14800 Chemical Structure

DW14800 Chemical Structure

CAS No. : 2243709-60-4

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Description

DW14800 is a protein arginine methyltransferase 5 (PRMT5) inhibitor, with an IC50 of 17 nM. DW14800 reduces H4R3me2s levels and enhances the transcription of HNF4α, but does not alter PRMT5 expression. Anti-cancer activity[1].

IC50 & Target

PRMT5[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

512.64

Formula

C₃₁H₃₆N₄O₃

CAS No.

2243709-60-4

SMILES

CN(C)C1=CC=C(C(N2CCC(C=C(C(NCC(O)CN3CC(C=CC=C4)=C4CC3)=O)C=C5)=C5C2)=O)C=C1

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Room temperature in continental US; may vary elsewhere

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Product Name:
DW14800
Cat. No.:
HY-128579
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DW14800

Cat. No.: HY-128579