2244622-44-2

MptpB-IN-1 Chemical Structure
2244622-44-2

Chemical Structure

MptpB-IN-1

  • CAS No.: 2244622-44-2
  • Formula:C17H11Cl2NO4
  • Molecular Weight:364.18

IUPAC Name: 4-(3',5'-dichloro-4'-hydroxy-[1,1'-biphenyl]-3-yl)-5-methylisoxazole-3-carboxylic acid

InChIKey: RHLHXHOGVCAPFR-UHFFFAOYSA-N

SMILES: O=C(C1=NOC(C)=C1C2=CC=CC(C3=CC(Cl)=C(C(Cl)=C3)O)=C2)O

Biological Activity: MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden[1].

Cat. No. Product Name Purity Description Pricing
HY-145741
MptpB-IN-1 99.98% MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden.
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