2244622-44-2
Chemical Structure
MptpB-IN-1
- CAS No.: 2244622-44-2
- Formula:C17H11Cl2NO4
- Molecular Weight:364.18
IUPAC Name: 4-(3',5'-dichloro-4'-hydroxy-[1,1'-biphenyl]-3-yl)-5-methylisoxazole-3-carboxylic acid
InChIKey: RHLHXHOGVCAPFR-UHFFFAOYSA-N
SMILES: O=C(C1=NOC(C)=C1C2=CC=CC(C3=CC(Cl)=C(C(Cl)=C3)O)=C2)O
Biological Activity: MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MptpB-IN-1 | 99.98% | MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden. | ||||||||||||||||||||
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Keywords