2244984-64-1
2244984-64-1
Chemical Structure
CSLP37
- CAS No.: 2244984-64-1
- Formula:C25H30FN5O3S
- Molecular Weight:499.60
IUPAC Name: N-(5-(2-amino-5-(4-(piperazin-1-yl)phenyl)pyridin-3-yl)-3-fluoro-2-methoxyphenyl)propane-1-sulfonamide
InChIKey: AMLGBGSXVKQKOZ-UHFFFAOYSA-N
SMILES: CCCS(=O)(NC1=CC(C2=CC(C3=CC=C(N4CCNCC4)C=C3)=CN=C2N)=CC(F)=C1OC)=O
Biological Activity: CSLP37 is a selective RIPK2 inhibitor with an IC50 of 16.3 nM. CSLP37 shows no inhibitory activity against RIPK1 and RIPK3. CSLP37 displays potent suppression of cellular NOD1 and NOD2 responses[1].
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CSLP37 | CSLP37 is a selective RIPK2 inhibitor with an IC50 of 16.3 nM. CSLP37 shows no inhibitory activity against RIPK1 and RIPK3. CSLP37 displays potent suppression of cellular NOD1 and NOD2 responses. | |||||||||||||||||||||
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References
Keywords
