2254176-11-7
2254176-11-7
Chemical Structure
Desmethyl Levofloxacin hydrochloride
- CAS No.: 2254176-11-7
- Formula:C17H19ClFN3O4
- Molecular Weight:383.80
IUPAC Name: (S)-9-fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride
InChIKey: IOFZKWNXVPUJLW-FVGYRXGTSA-N
SMILES: O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CCNCC4)C(F)=CC1=C23)O.Cl
Biological Activity: Desmethyl Levofloxacin hydrochloride is a metabolite of Levofloxacin (HY-B0330). Levofloxacin is a synthetic fluoroquinolone antibiotic that inhibits the supercoiling activity of bacterial DNA gyrase and prevents DNA replication[1][2].
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Desmethyl Levofloxacin hydrochloride | Desmethyl Levofloxacin hydrochloride is a metabolite of Levofloxacin (HY-B0330). Levofloxacin is a synthetic fluoroquinolone antibiotic that inhibits the supercoiling activity of bacterial DNA gyrase and prevents DNA replication. | |||||||||||||||||||||
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References
- [1]. Siva R, et al. Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. International journal of chronic obstructive pulmonary disease. 2014;9:179-86. [Content Brief]
- [2]. Zheng YJ, et al. An integrated approach for detection and characterization of the trace impurities in levofloxacin using liquid chromatography-tandem mass spectrometry. Rapid communications in mass spectrometry : RCM. 2014 May 30;28(10):1164-74.
Keywords
