2260542-60-5
Chemical Structure
OSMI-2
- CAS No.: 2260542-60-5
- Formula:C26H25N3O7S2
- Molecular Weight:555.62
IUPAC Name: methyl (R)-N-(2-(2-methoxyphenyl)-2-((2-oxo-1,2-dihydroquinoline)-6-sulfonamido)acetyl)-N-(thiophen-2-ylmethyl)glycinate
InChIKey: ACLDUOSWRUIOSB-RUZDIDTESA-N
SMILES: O=C(OC)CN(C([C@@H](C1=CC=CC=C1OC)NS(=O)(C2=CC3=C(NC(C=C3)=O)C=C2)=O)=O)CC4=CC=CS4
Biological Activity: OSMI-2 (Compound 1b) is a cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-2 increases detained intron splicing in cells[1].
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OSMI-2 | 99.59% | OSMI-2 (Compound 1b) is a cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-2 increases detained intron splicing in cells. | ||||||||||||||||||||
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Keywords